An introduction to systems biology :

Alon, Uri, 1969-

An introduction to systems biology : design principles of biological circuits / Uri Alon. - Second edition. - xviii, 324pages ; ill., 26 cm.

Includes bibliographical references and index.

Part one: Network motifs -- Transcription networks basic concepts -- Autoregulation -- The feed forward loop -- Temporal programs and the global structure of transcription networks -- Positive feedback, bistability and memory -- How to build a biological oscillator -- Robustness -- Kinetic proofreading and conformational proofreading -- Part two: Robust signalling -- Chemotaxis -- Fold-change detection -- Dynamical compensation and mutal resistance in tissues -- Robust spatial patterning in development -- Part three: Optimality -- Optimal gene circuit design -- Multi-objective optimality in biology -- Modularity.

9781439837177

2019003924


Systems biology.
Computational biology.
Biological systems--Mathematical models.

QH324.2 / .A46 2019

570.113 / ALO