TY  - BOOK
AU  - Alon,Uri
TI  - An introduction to systems biology: design principles of biological circuits 
SN  - 9781439837177
AV  - QH324.2 .A46 2019
U1  - 570.113 23
PY  - 2019///]
CY  - Boca Raton, Fla.
PB  - CRC Press
KW  - Systems biology
KW  - Computational biology
KW  - Biological systems
KW  - Mathematical models
N1  - Includes bibliographical references and index; Part one: Network motifs -- Transcription networks basic concepts -- Autoregulation -- The feed forward loop -- Temporal programs and the global structure of transcription networks -- Positive feedback, bistability and memory -- How to build a biological oscillator -- Robustness -- Kinetic proofreading and conformational proofreading -- Part two: Robust signalling -- Chemotaxis -- Fold-change detection -- Dynamical compensation and mutal resistance in tissues -- Robust spatial patterning in development -- Part three: Optimality -- Optimal gene circuit design -- Multi-objective optimality in biology -- Modularity
ER  -